Structure/Function Analysis ofrasUsing Random Mutagenesis Coupled with Functional Screening Assays*
نویسندگان
چکیده
منابع مشابه
Functional assays for screening GPCR targets.
G-protein-coupled receptors (GPCRs) are valuable molecular targets for drug discovery. An important aspect of the early drug discovery process is the design and implementation of high-throughput GPCR functional assays that allow the cost-effective screening of large compound libraries to identify novel drug candidates. Several functional assay kits based on fluorescence and/or chemiluminescence...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 1987
ISSN: 0888-8809,1944-9917
DOI: 10.1210/mend-1-2-127